AT2R Agonist, Compound 21, Is Reno-Protective Against Type 1 Diabetic Nephropathy
نویسندگان
چکیده
منابع مشابه
AT2R agonist, compound 21, is reno-protective against type 1 diabetic nephropathy.
The hemodynamic and nonhemodynamic effects of angiotensin II on diabetic complications are considered to be primarily mediated by the angiotensin II type 1 receptor subtype. However, its biological and functional effect mediated through the angiotensin II type 2 receptor subtype is still unclear. Activation of the angiotensin II type 2 receptors has been postulated to oppose angiotensin II type...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2015
ISSN: 0194-911X,1524-4563
DOI: 10.1161/hypertensionaha.115.05204